IndraLab

Statements


USP7 deubiquitinates Histone_H3. 2 / 2
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"USP7 stabilizes several other histone associated proteins including acetyltransferase TIP60, demethylase PHF8, methyltransferase MLL5, lysine specific demethylase 1 (LSD1 and KDM1), and directly deubiquitinates histone H3."

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"Our results thus suggest that histone H3 deubiquitylation by Usp7 is an important step in the maintenance of DNA methylation."