IndraLab

Statements

Hydroxychloroquine decreases the amount of CD40LG. 4 / 4
1 | 3
reach
"Chloroquine and hydroxychloroquine can inhibit major histocompatibility complex class II expression, antigen presentation and immune activation (reducing CD154 expression by T cells) via Toll-like receptor signalling and cGAS stimulation of interferon genes [11]."
32305588
ctd
No evidence text available
28793932
reach
"Hydroxychloroquine and chloroquine, the commonly used therapeutic drugs for RA, have also been demonstrated to inhibit autophagy by preventing immune activation and cytokine production of various cells and regulating the expression of CD154 on T cells (96)."
35003139
reach
"HCQ and CQ can prevent the antigen processing, T-cell activation, TLR-cyclic GMP-AMP Synthase (cGAS), CD154 expression and down-regulate the pro-inflammatory genes [391]."
34710479