IndraLab

Statements

CD44 binds SLC7A11 and OTUB1. 3 / 3
| 3
sparser
"Thus, OTUB1 and CD44 interacts with the different domains of SLC7A11."
30709928
sparser
"Since CD44 can stabilize SLC7A11 by enhancing the binding between SLC7A11 and OTUB1 ( xref ), it is very likely that CD44, OTUB1 and SLC7A11 form a stable three-protein complex that leads to more effective stabilization of SLC7A11."
30709928
sparser
"By the same method, to avoid the issue that decreased SLC7A11 protein levels are the only factor for the decrease of the OTUB1-SLC7A11 interaction in CD44 knockdown cells (Input: lane 1 vs. lane 2, xref ), we normalized the amounts of SLC7A11 after immunoprecipitation (IP: lane 3 vs. lane 4, xref )."
30709928