IndraLab

Statements

OTUD5 activates apoptotic process. 4 / 4
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reach
"The function of OTUD5 is required to allow the rapid activation of p53 dependent transcription and a p53 dependent apoptosis in response to DNA damage stress."
24143256
eidos
"It was proved that OTUD5 inhibited the proliferation and metastasis of NSCLC cells but promoted their apoptosis via regulating p53 and PDCD5 ."
| PMC
reach
"To study the cellular consequence of specifically blocking the interaction between OTUD5 and FACT (OTUD5 overexpression or complete knockout causes aberration in cell cycle and apoptosis), we generated a HeLa knock-in (KI) cell line in which the D537A mutation is introduced into the genomic loci of OTUD5 (OTUD5 ) using the CRISPR-Cas9 method (Supplementary Figure S2; sequencing information of 4 clones)."
37713620
eidos
"Knockdown of OTUD5 accelerated the proliferation , migration , and invasion of A549 cells , and inhibited their apoptosis Next , A549 cells were used for the following experiment ."
| PMC