IndraLab

Statements



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"Despite this cost in fitness, these mutants are not more susceptible to a wide range of antibiotics; including ribosome targeting antibiotics, such as lincomycin, chloramphenicol, and streptomycin, which have been shown previously to disrupt EF-P function in vitro."

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"Interestingly, streptomycin at 2 x 10-5 M, which causes misreading and also inhibits A-site occupation of the a type [17], is a potent inhibitor of the EF-P mediated reaction."