IndraLab

Statements


Phosphorylated TSC2 is active. 5 / 5
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"Gsk3 inhibits the mtor pathway by phosphorylating tsc2 in a manner dependent on ampk-priming phosphorylation."

"Gsk3 inhibits the mtor pathway by phosphorylating tsc2 in a manner dependent on ampk-priming phosphorylation."

"However, AMP-activated protein kinase (AMPK), an essential cellular energy sensor, phosphorylates and activates TSC2 [ xref ]."

"SGK3 phosphorylates six sites on TSC2 to activate mTORC1 in an AKT-independent manner."

"Gsk3 inhibits the mtor pathway by phosphorylating tsc2 in a manner dependent on ampk-priming phosphorylation."