IndraLab

Statements


PAN2 deubiquitinates ASF1A. 5 / 5
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"Interestingly, we demonstrate that USP52 is a bona fide ubiquitin specific protease, and USP52 promotes ASF1A deubiquitination and stabilization."

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"Since ASF1A is reported as a ubiquitinated protein 49, we then asked whether USP52 functions to deubiquitinate ASF1A."

"Additionally, we find that USP52 is overexpressed in breast carcinomas, and its level of expression correlates with that of ASF1A."

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"USP52 deubiquitinates ASF1A."

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"Nevertheless, our study identified that USP52 is a bona fide USP, and revealed that USP52 deubiquitinates and stabilizes histone chaperone ASF1A."