IndraLab

Statements


EGF leads to the sumoylation of OTUB2. 5 / 5
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sparser
"Furthermore, OTUB2 sumoylation is stimulated by EGF and oncogenic KRAS, which is essential for EGF and KRAS to stabilize Yap/Taz ( xref )."

sparser
"Importantly, EGF and oncogenic KRAS induce OTUB2 poly-SUMOylation and thereby activate YAP/TAZ."

sparser
"Importantly, EGF and oncogenic KRAS induce OTUB2 poly-SUMOylation and thereby activate YAP/TAZ."

reach
"Poly-SUMOylated OTUB2, which was induced by Epidermal growth factor (EGF) and oncogenic KRAS, was shown to bind and activate YAP/TAZ promoting tumor metastasis [68]."

reach
"Importantly, EGF and oncogenic KRAS induce OTUB2 poly-SUMOylation and thereby activate YAP and TAZ."