IndraLab

Statements

P5091 activates DDX53. 3 / 3
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"A selective USP7 inhibitor, P5091, effectively inhibits CT26 xenograft growth in mice, similar to anti-PD-1 antibody treatment [93]."
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"32 Our study here aimed to examine the effect of P5091 on antitumor immunity and its possible role in cancer immunotherapy.In our study, we found that P5091 promoted colon cancer cell apoptosis and death in CT26 xenografted mice and that the effect was similar when compared to an anti-PD-1-treated group."
30697058
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"Compound P5091, a selective USP7 inhibitor, was found to inhibit CT26 xenografts growth in mice, which is comparable to the effect of Anti-PD-1 antibody."
30697058