IndraLab

Statements

USP4 is methylated. 2 / 2
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"Metformin attenuates multiple myeloma cell proliferation and encourages apoptosis by suppressing METTL3-mediated m6A methylation of THRAP3, RBM25, and USP4."
36762777
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"Moreover, we identified that METTL3 could methylate USP4 at one m 6 A site within the CDS and around the stop codon, and the m 6 A reader protein YTHDF2 could recognize the m 6 A site and then recruit RNA-binding protein HNRNPD to the mRNA, resulting in degradation of USP4 mRNA."
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