IndraLab

Statements


ZRANB1 activates Wnt. 3 / 3
| 3

reach
"Although Trabid was first reported to activate the Wnt pathway by cleavage of the K63 linked chains, it was recently demonstrated to be 40-fold more active toward the K29 linked chains."

reach
"TRABID, one of K63 specific DUB enzymes, became an attractive candidate to achieve this task since it has been reported to regulate Wnt signal positively [XREF_BIBR], as inhibition of TRABID presumably decreases Wnt signaling activity."

reach
"However, in this study, we failed to confirm the notion that TRABID positively regulates canonical Wnt signaling based on several lines of evidence."