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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

PML inhibits USP7. 3 / 3

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"47 In addition, PML negatively regulates the function of HAUSP through DAXX to further modulate PTEN activity in a context specific manner."

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"PML is required to inhibit USP7, thus preventing the deubiquitination of the tumor suppressing phosphatase PTEN."

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"Conversely, PML negatively regulates the DUB HAUSP and USP7, thus opposing PTEN deubiquitination and cytoplasmic translocation."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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Statements

PML inhibits USP7. 3 / 3

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