IndraLab

Statements


EIF3F is phosphorylated on S258. 5 / 5
1 | 4

sparser
"We found that an isoform of CDK11 (CDK11/p58), which exists in large amounts only during M phase, inhibits cap-dependent translation through the phosphorylation of Thr255 and/or Ser258 in eIF3F, a subunit of eIF3."

sparser
"CDK11/p58 phosphorylates Thr255 and/or Ser258 of eIF3F."

No evidence text available

sparser
"Phosphorylation of Thr255 and/or Ser258 in eIF3F by CDK11/p58 resulted in global translational repression in M phase."

sparser
"The data indicate that translation is globally repressed about 50% in M phase cells and that phosphorylation of Thr255 and/or Ser258 in eIF3F by CDK11/p58 plays a major role in the M phase-specific translational repression."