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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

COPS5 leads to the deubiquitination of TP53. 1 / 1

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"The protein CSN5, a part of the COP9 signalosome and a regulator of cell cycle proteins such as p27, has been shown to increase p53 proteasomal degradation by promoting p53 nuclear export and decreasing MDM2 auto-ubiquitination and degradation XREF_BIBR."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...