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COPS5 leads to the deubiquitination of TP53. 2 / 2

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"For instance, Jab1/CSN5 promotes the ubiquitination and degradation of p53 and antagonizes the transcriptional activity of p53 ."

35315259

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"The protein CSN5, a part of the COP9 signalosome and a regulator of cell cycle proteins such as p27, has been shown to increase p53 proteasomal degradation by promoting p53 nuclear export and decreasing MDM2 auto-ubiquitination and degradation XREF_BIBR."

23885265

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IndraLab

Statements

COPS5 leads to the deubiquitination of TP53. 2 / 2

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