IndraLab

Statements

BTRC inhibits USP33. 3 / 3
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"Deubiquitinase USP33 is negatively regulated by beta-TrCP through ubiquitin dependent proteolysis."
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"Thus, our data revealed a new regulatory mechanism of the deubiquitinase USP33, and uncovered an additional signaling pathway, that is, beta-TrCP downregulates USP33 to promote cell proliferation.HeLa[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"The results showed that knockdown of beta-TrCP in cells slowed down the degradation rate of endogenous USP33 and therefore enhanced USP33 protein stability."
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