IndraLab

Statements


USP44 activates FOXP3. 4 / 4
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"These results suggest that Tregs devoid of USP44 mediated FOXP3 stabilization are ineffective suppressors of anti-tumor immune responses."

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"Suspecting that USP44 targets FOXP3 for deubiquitination, we again utilized a co-IP approach to test this notion."

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"Combined USP7 and USP44 knockdown, however, even further enhanced FOXP3 degradation (Fig XREF_FIG D, left panel)."

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"USP44 promotes FOXP3 stabilization through deubiquitination."