IndraLab

Statements

IFNB1 increases the amount of USP18. 4 / 5
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"Finally, AA homozygosis for the intronic polymorphism rs2542109 was associated with the responder phenotype; however, USP18 expression levels induced by IFNbeta did not differ amongst MS patients carrying different rs2542109 genotypes."
23700969
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"XREF_BIBR, XREF_BIBR MS. IFN-beta is considered the first line of therapy against MS. XREF_BIBR, XREF_BIBR IFN-beta can induce USP18 expression through IFNAR."
27809302
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"77,78 IFN-β can induce USP18 expression through IFNAR."
27809302
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"On the other hand, the upregulation of USP18 inhibits beta cell apoptosis.75, 76IFN-β is considered the first line of therapy against MS.77, 78 IFN-β can induce USP18 expression through IFNAR."
27809302