IndraLab

Statements


IFNB1 increases the amount of USP18. 2 / 3
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"XREF_BIBR, XREF_BIBR MS. IFN-beta is considered the first line of therapy against MS. XREF_BIBR, XREF_BIBR IFN-beta can induce USP18 expression through IFNAR."

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"Finally, AA homozygosis for the intronic polymorphism rs2542109 was associated with the responder phenotype; however, USP18 expression levels induced by IFNbeta did not differ amongst MS patients carrying different rs2542109 genotypes."