IndraLab

Statements

KCNH1 activates cell cycle. 5 / 5
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"In addition, the short-hairpin RNA (shRNA)-mediated silencing of EAG1, a voltage-gated potassium channel, was found to inhibit proliferation and cell cycle progression in osteosarcoma [ 9 ]."
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"Eag1 Silencing Inhibits Cell Cycle Progression of Liposarcoma Cells."
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"Knockdown of Eag1 inhibited the GC cell proliferation, whereas knockdown of Eag1 decreased G -S phase cell cycle progression."
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"To analyze how Eag1 modulates OS cell proliferation and cell cycle progression, it is important to note that Eag1 contributes to tumor progression independently of its primary function as an ion channel."
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"Kv10.1 also aids cell cycle progression by stabilizing the membrane potential in the G1 phase and enhances invasiveness by modulating focal adhesions (Hartung, 2011)."
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