IndraLab

Statements


USP9X activates NRAS. 2 / 2
| 2

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"In two melanoma cell lines (SK-Mel29, WM1366; XREF_FIG), Usp9x activated NRAS promoter activity by ~ 2-fold, while Ets-1 expression increased promoter activity by> 2.5-fold."

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"Thus, Usp9x modulates the Ets-1 and NRAS regulatory network and may have biologic and therapeutic implications."