IndraLab

Statements

USP18 activates Protease. 3 / 3
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"A novel interferon stimulated gene encoding a 43-kDa ubiquitin specific protease, designated ISG43, was identified in this screen."
10722734
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"The IFN stimulated gene ubiquitin specific proteinase 18 (USP18) encodes a protein that negatively regulates T1 IFN signaling via stearic inhibition of JAK1 recruitment to the IFN-alpha receptor 2 subunit (IFNAR2)."
29437254
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"The IFN-stimulated gene ubiquitin specific proteinase 18 (USP18) encodes a protein that negatively regulates T1 IFN signaling via stearic inhibition of JAK1 recruitment to the IFNα receptor 2 subunit (IFNAR2)."
29437254