IndraLab

Statements

HCN4 inhibits Heart Rate. 2 / 2
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"We observed several distinct alterations in protein expression or activity likely to impact HR in parallel : (1) Hcn4 mRNA was significantly downregulated in TG mice, suggesting TBC1D10C controls HR via regulation of I f; (2) CaMKII activity is reduced."
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"Beat-to-beat HR variability was reduced by HCN4 overexpression and enhanced by HCN4 knockdown."
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