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Parkinson Disease inhibits USP1. 3 / 3

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"An in vitro assay with purified rDUB showed that PD inhibited USP1/UAF1 activity."

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"PD inhibits USP1/UAF1 activity with an IC50 value of 2.536e-005 M (Figure 4C)."

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"PD also blocked more than 50% of the DUB activity of USP1, but not USP2 [160]."

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Parkinson Disease inhibits USP1. 3 / 3

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