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EIF3F activates STING1. 1 / 2

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"Additionally , iRhom2 protein assembles the deubiquitinase eukaryotic translation initiation factor 3S5 ( EIF3S5 ) , which acts to promote STING during this process.117 STING relocation from the ER and interaction with TBK1 in the perinuclear area , prompts the activation of IRF3 through phosphorylation.120 TBK1 phosphorylates the tail domain of the carboxy-terminal from STING , resulting in the assembly of IRF3 and its subsequent phosphorylation ."

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EIF3F activates STING1. 1 / 2

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