IndraLab

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SIRT1 inhibits USP22. 2 / 2

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"Mechanistically, KLF3-AS1 inhibited the ubiquitination of Sirt1 protein through inducing USP22."

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"In particular, SIRT1 stabilization is due to the overexpression, in HCC, of lncRNA HULC (highly upregulated in liver cancer) through a mechanism in which HULC inhibits SIRT1 ubiquitination and degrada[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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IndraLab

Statements

SIRT1 inhibits USP22. 2 / 2

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