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OTUD4 inhibits SMURF2. 1 / 1

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"Specifically, we find that OTUD4 enhances TGFβ signalling by promoting the membrane presence of TGFβ receptor I. Furthermore, we demonstrate that OTUD4 inactivates the TGFβ negative regulator SMURF2 suggesting that OTUD4 regulates multiple nodes of the TGFβ pathway to enhance TGFβ activity."

32973272

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IndraLab

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OTUD4 inhibits SMURF2. 1 / 1

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