IndraLab

Statements

USP7 activates cell migration. 15 / 15
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"These data suggested that USP7 increased cell migration and invasion abilities by inducing EMT of OSCC cells."
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"In OSCC cells, USP7 was shown to promote cell proliferation, inhibit apoptosis, enhance cell migration and invasion, and activate the Akt/ERK pathway."
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"The migration capacity of HCC cells was also tested by wound healing assay, revealing that USP7 can promote tumor cell migration (XREF_FIG)."
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"Next, biological function assays demonstrated that USP7 knockdown markedly inhibited OS cell migration and invasion, whereas USP7 overexpression enhanced it."
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"USP7 promotes malignancy of OSCC cells via activating Akt / ERK signaling pathway The present data showed that USP7 could promote OSCC cell migration and invasion ."
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"USP7 promotes cell migration , invasion , and sphere formation in part through EZH2 stabilization In prostate cancer , USP7 overexpression has been reported to show a direct correlation with tumor aggressiveness ( Song et al ., 2008 ) ."
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"These data suggested that USP7 increased cell migration and invasion abilities by inducing EMT of OSCC cells ."
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"After seeing that USP7 knockdown inhibits MKN45 cell migration, we investigated the status of mesenchymal marker proteins."
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"USP7 has been shown to induce prostate cancer cell migration and invasion by stabilizing the Enhancer of Zeste homolog 2 (EZH2) gene."
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"The Transwell assays showed that overexpression of USP7 promotes NSCLC cell migration in both cell lines (Figure S1A), which was consistent with the previous finding that c‐Abl contributes to cancer metastasis."
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"Suppression of OSCC cell migration and invasion by USP7 knockdown."
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"In OSCC cells , USP7 was shown to promote cell proliferation , inhibit apoptosis , enhance cell migration and invasion , and activate the Akt / ERK pathway ."
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"The present data showed that USP7 could promote OSCC cell migration and invasion."
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"Moreover, knockdown of USP7 and c‐Abl also inhibited NSCLC cell migration (Figure S1C)."
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"Wound healing and transwell assays revealed that knockdown of USP7 or YY1 inhibited cell migration and invasion, and double knockdown enhanced this suppression effect in HCT116 (Fig. 6A–C), LOVO (Fig. 6D–F), and DLD1 cells (Fig. 6G–I)."
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