IndraLab

Statements


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"Another short peptide extension found at the amino terminus of SLO appears to contribute to the SLO mediated transport of another protein across the membrane of a eukaryotic cell [XREF_BIBR, XREF_BIBR]."

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"The loss of flow-induced [Ca 2+ ] i transients in ICs and BK channel-mediated FIKS in microperfused collecting ducts isolated from mice with IC-specific deletion of Piezo1 in the CCD underscores the importance of PIEZO1 in the renal regulation of K + transport."

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"The use of lower SLO concentrations required longer enzyme activation at 37°C and significantly reduced the efficiency in recycling transport reconstitution."

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"These results suggest that BK channel mediated FIKS is dependent on a basolateral bumetanide sensitive, Cl dependent transport pathway, proposed to be NKCC1, in both IC and PC in the CCD."

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"The cells were then SLO permeabilized and further incubated for 2 h at 37degreesC to allow the transport of the spike glycoproteins to the plasma membrane."

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"In addition, SLO has been shown to mediate vectorial transport of streptococcal proteins into the cytoplasm of host cells."

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"In this pathway, KCNMA1 and SLC12A2 primarily contribute to the transport of Ca , Cl , and HCO , maintaining a normal physiological environment."