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MK-499 inhibits KCNH2. 1 / 1

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"Astemizole, terfenadine, cisapride, and MK-499 inhibited cERG and human ERG (hERG) currents with IC (50) values of 1.3, 13, 19, and 15 nM and 1.2, 9, 14, and 21 nM, respectively, and competitively displaced [(35) S] MK-499 binding from cERG and hERG with IC (50) values of 0.4, 12, 35, and 0.6 nM and 0.8, 5, 47, and 0.7 nM, respectively."

12388285

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MK-499 inhibits KCNH2. 1 / 1

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