IndraLab

Statements


1 | 6

sparser
"Interestingly, interaction of CAM with the intracellular domain of the full-length ACE2 inhibited ACE2 shedding, suggesting a role for the ACE2 intracellular domain in regulating the cleavage of its ectodomain (82, 83)."

sparser
"The connection of ACE2 to calmodulin 1 (CALM1) is based on a publication by Lambert et al.36 in which they show that CALM1 interacts with the corona virus receptor ACE2 and inhibits shedding of its ectodomain36."

sparser
"Analysis of the alterations in connections between seed genes showed also affected ACE2-CALM1 interaction (RankDelta = 60, Rank X = 155) and AGT-MME (Rank Delta = 85, RankX = 63)."

sparser
"6) If CAM interacts with the transmembrane full-length ACE2, the shedding of ACE2 may be abrogated."

sparser
"Interestingly, interaction of CAM with the intracellular domain of the full-length ACE2 inhibited ACE2 shedding, suggesting a role for the ACE2 intracellular domain in regulating the cleavage of its ectodomain ( xref , xref )."

No evidence text available

sparser
"The connection of ACE2 to calmodulin 1 (CALM1) is based on a publication by Lambert et al. 25 in which they show that CALM1 interacts with the corona virus receptor ACE2 and inhibits shedding of its ectodomain 25 ."
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