IndraLab

Statements

CALM1 binds ACE2. 8 / 8
2 | 6
sparser
"Interestingly, interaction of CAM with the intracellular domain of the full-length ACE2 inhibited ACE2 shedding, suggesting a role for the ACE2 intracellular domain in regulating the cleavage of its ectodomain ( xref , xref )."
34163462
sparser
"Calmodulin antagonists inhibit CALM-ACE2 interaction and increase the release of the ACE2 ectodomain in a dose- and time-dependent manner [ xref ]."
| PMC
sparser
"Calmodulin (CALM) antagonists inhibit the CALM–ACE2 interaction and increase the release of the ACE2 ectodomain in a dose- and time-dependent manner [117]."
| PMC
biogrid
No evidence text available
19164471
sparser
"Analysis of the alterations in connections between seed genes showed also affected ACE2-CALM1 interaction (RankDelta = 60, Rank X = 155) and AGT-MME (Rank Delta = 85, RankX = 63)."
33233425
sparser
"It has been exhibited that CALM, a ubiquitous calcium-binding protein, interacts with ACE2 and inhibits its ADAM17-dependent ectodomain shedding."
| PMC
sparser
"The connection of ACE2 to calmodulin 1 (CALM1) is based on a publication by Lambert et al. 25 in which they show that CALM1 interacts with the corona virus receptor ACE2 and inhibits shedding of its ectodomain 25 ."
| DOI
biogrid
No evidence text available
18070603