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FBXO42 inhibits USP28. 1 / 1
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"Genetic ablation of FBXO42 or CCDC6 in PANC-1 cells also reduced USP28 protein abundance, without affecting USP28 transcript levels (Fig. 3I; Appendix Fig. 5C), indicating that the post-translational regulation of USP28 by FBXO42/CCDC6 is not unique to RPE1 cells."