IndraLab

Statements

USP3 activates Neoplasms. 9 / 10
| 1 8
reach
"Functional studies further demonstrated that USP3 promotes osteosarcoma cell proliferation and tumor growth both in vitro and in vivo."
40179740
reach
"USP3, as a deubiquitinating enzyme, mediates tumor progression mainly by deubiquitinating and modifying downstream target proteins."
38531846
reach
"Additionally, Wu et al. constructed a USP3 knockdown xenograft tumor model of breast cancer, demonstrating that a decrease in USP3 significantly inhibited tumor growth compared with the control group."
38651282
reach
"USP3 knockdown inhibited tumor growth, while co-overexpression of SMARCA5 significantly rescued this effect (Fig. 5E–G)."
39500888
reach
"Depletion of USP3 significantly represses mouse xenograft tumor growth."
38651282
reach
"As shown in Fig. 6G–I, depletion of USP3 or docetaxel treatment similarly inhibited tumor growth, whereas the combined silencing of USP3 and docetaxel treatment did further reduce tumor growth in the xenograft model."
39500888
reach
"Additionally, overexpressed USP3 significantly promoted cell proliferation in vitro and tumor growth in vivo, while the silencing of USP3 inhibited proliferation and tumor growth."
36792297
reach
"Nagy et al. reported that USP3 promotes neuroblastoma cell viability, proliferation, and xenograft tumor growth by cleaving K48‐ and K63‐linked ubiquitin chains of MYCN (Figure 2C, right)."
38651282
eidos
"Our previous study revealed that USP3 promotes tumour progression and is highly expressed in gastric cancer ( GC ) ."
34930901