IndraLab

Statements

UCHL3 activates XRCC5. 2 / 2
| 2
reach
"ATM-dependent phosphorylation of the deubiquitinase UCHL3 enables UCHL3 to enhance the retention of Ku80 at damage sites by counteracting Ku80 ubiquitination (Nishi et al., 2018)."
39050891
reach
"In accordance with reduced Ku80 IRIF, we observed that knockout and knockdown of UCHL3 reduced DSB-induced chromatin binding of Ku80 using chromatin fractionation until 3 hours after phleomycin removal (Fig. 4C and Supplementary Fig. S5)."
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