IndraLab

Statements

Resveratrol inhibits RELA. 21 / 21
12 | 9
reach
"Resveratrol inhibits the progression of premature senescence partially by regulating v-rel avian reticuloendotheliosis viral oncogene homolog A (RELA) and sirtuin 1 (SIRT1)."
35166167
reach
"Moreover, resveratrol treatment significantly reduced eosinophil counts, p65, Interferon-gamma, interleukin (IL)-5, IL-33, and tumor necrosis factor-alpha levels, matrix metalloproteinase-9 activity, claudin-5 degradation, and blood-brain barrier permeability."
28545897
ctd
No evidence text available
22246136
reach
"Resveratrol reduced the transcriptional activity of p65, but neither affected the DNA binding activity of NF-kappaB nor blocked the nuclear translocation of p65."
24020126
ctd
No evidence text available
19047049
reach
"Furthermore, combined curcumin and resveratrol significantly inhibited TNF-α-induced nuclear factor-kappaB (NF-κB) p65 nuclear protein expression than that by the individual chemical alone in EA.hy 926 cells, indicating that the synergistic effect of the combination may result from that curcumin reduces the required minimum concentration for resveratrol to inhibit the nuclear translocation of NF-κB."
35691595
ctd
No evidence text available
22363816
reach
"Treatment of LPS-stimulated RAW264.7 cells with resveratrol-enriched rice seed extracts (DJ526_0 and DJ526_5) significantly decreased the production of nitric oxide (NO) and the inflammatory mediator prostaglandin E2 (PGE 2 ), downregulated proinflammatory gene expression, and inhibited nuclear factor kappa B (NF-κB) p65, p38 mitogen-activated protein kinase, and extracellular signal-regulated kinase 1/2 (ERK 1/2) phosphorylation."
37446559
ctd
No evidence text available
17938187
ctd
No evidence text available
16490592
ctd
No evidence text available
24020126
reach
"To our knowledge, this study is the first to reveal that resveratrol targeting protein NQO2 plays a mediating role in resveratrol induced changes of NF-kappaB p65, which may contribute to the anti-CaP activities elicited by resveratrol."
19661309
ctd
No evidence text available
11858183
ctd
No evidence text available
21239502
ctd
No evidence text available
19284563
reach
"The results showed that resveratrol, the activator of SIRT1, inhibited the binding of NF-kappaB p65 to the MMP-13 promoter, and the situation was the opposite after being treated with the inhibitor of SIRT1."
28473882
reach
"The activation of SIRT1 by resveratrol, leading to the inhibition of phospho-p38 MAPK as well as the reduced NF-kappaB p65 activity [XREF_BIBR]."
| PMC
reach
"Furthermore, resveratrol also inhibited the appearance of subunit p65 in the nucleus [XREF_BIBR]."
27834913
ctd
No evidence text available
20675566
ctd
No evidence text available
17164350
ctd
No evidence text available
18222423