IndraLab

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USP38 activates cell population proliferation. 11 / 11
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"Conversely, knockdown of USP38 effectively inhibited the proliferation of A549 and Hela cells ( Fig. 3 C and D)."
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"The effect of USP38 on promoting cell proliferation only occurred in control A549 cells, but not in c-Myc knockdown A549 cells ( Fig. 3 E)."
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"Conversely, in gastric cancer (GC), USP38 is overexpressed and promotes the proliferation and migration of GC cells, facilitating GC progression by stabilizing FASN [35]."
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"Functionally, USP38 promotes cell proliferation in a c-Myc dependent manner."
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"Functionally , USP38 is able to promote cell proliferation via a c-Myc dependent manner ."
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"In this research, we found that USP38 was overexpressed in GC tissues, and USP38 contributed to GC cell proliferation, migration and tumorigenesis."
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"USP38 silencing suppresses the proliferation of LUAD cells in vitro and impedes the tumorigenic activity of cells in xenograft mouse models in vivo."
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"In addition, USP38 has been shown to promote cell proliferation by stabilizing LSD1 or c-Myc proteins27, 28."
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"On the other hand, USP38 is able to promote cell proliferation and asthmatic pathogenesis, seeming to be an oncogenic factor ( Chen et al., 2018 ; Liu et al., 2018 )."
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"In addition, USP38 promotes lung cancer cell proliferation by stabilizing c-Myc (14)."
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"In this study, we show that silencing USP38 inhibits ESCC cell proliferation and growth in vitro and in vivo."
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