IndraLab

Statements

USP29 increases the amount of VIM. 3 / 3
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"As shown in Figure S3A,B (Supporting Information), the stable expression of USP29 decreased the expression of epithelial marker E‐cadherin and increased the expression of mesenchymal marker Vimentin."
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"Of note, the depletion of USP29 in both MDA‐MB‐231 and BT549 cells significantly decreased the expression of TWIST1 and Vimentin, and increased the expression of epithelial marker E‐cadherin (Figure 3A; Figure S3C,D, Supporting Information), while the reconstitution of TWIST1 in USP29‐deficient cells could dramatically rescue such a change (Figure 3A)."
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"As shown in Figure S6G,H (Supporting Information), the stable overexpression of USP29 in luminal breast cancer cell MCF‐7 decreased the level of epithelial marker E‐cadherin and increased the expression of mesenchymal marker Vimentin, whereas the 3A mutant failed to induce such phenotypes."
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