IndraLab

Statements


MPND activates DEG15. 2 / 2
| 2

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"First, the indolactam specific TleC and MpnD both accepted DMAPP (C 5) and GPP (C 10) as substrates to produce pendolmycin (3), and lyngbyatoxin A (2) and 5-geranylindolactam V (4) (2:4 = 26:1 for TleC; 2:4 = 1:3 for MpnD), respectively (XREF_FIG)."

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"Thus, TleC and MpnD clearly prefer to accept GPP and DMAPP as the prenyl donors, respectively."