IndraLab

Statements


STAMBP leads to the deubiquitination of RAI14. 3 / 3
| 3

reach
"As expected, overexpression of STAMBP rescued the ubiquitination of RAI14 caused by STAMBP knockdown (Fig. 3i)."

reach
"However, overexpression of STAMBP with a catalytically inactive site (D348A) failed to decrease the ubiquitination of the RAI14 protein (Supplementary Fig. 2), supporting the hypothesis that STAMBP DUB activity is required for RAI14 deubiquitination."

reach
"Recent studies have shown that the deubiquitinase STAMBP suppresses the ubiquitination of RAI14 and stabilizes its protein level, thereby promoting breast cancer progression (Yang et al, 2022)."