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KCNK2 activates cell differentiation. 2 / 2
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"Furthermore, TREK-1 knockdown and fluoxetine administration directly reduced the differentiation of fibroblasts to myofibroblasts by inhibiting the focal adhesion kinase (FAK)/p38 mitogen-activated protein kinases (p38)/Yes-associated protein (YAP) signaling pathway."
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"7 The resulting increase in the proteins Sox9, osteopontin and collagen provided evidence that a mechanical stimulation of TREK-1 is sufficient to induce the differentiation of osteoprogenitor cell populations toward an osteogenic lineage."
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