IndraLab

Statements

Progesterone inhibits NFKB1. 3 / 4
1 | 3
reach
"High levels of estradiol, HCG and progesterone during the pregnancy can inhibit secretion of such NFkB induced inflammatory cytokines as IL-1, -2, -3, -5, -8, interferon-gamma (IFN-gamma) and tumor necrosis factor-alpha (TNF-alpha) by Mphis and T cells, while enhance the secretion of the monocyte deactivating cytokine, IL-10 [XREF_BIBR - XREF_BIBR]."
19683334
reach
"It has been proposed that progesterone might also decrease NFkB mediated inflammatory transcription [6]."
17437195
reach
"It has also been proposed that at an earlier step of the innate immune response, progesterone may suppress the Toll like receptors (TLR), and likewise antagonize NFkB signaling [26]."
17437195