IndraLab

Statements

Progesterone inhibits NFKB1. 4 / 4
1 | 3
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"High levels of estradiol, HCG and progesterone during the pregnancy can inhibit secretion of such NFkB induced inflammatory cytokines as IL-1, -2, -3, -5, -8, interferon-gamma (IFN-gamma) and tumor necrosis factor-alpha (TNF-alpha) by Mphis and T cells, while enhance the secretion of the monocyte deactivating cytokine, IL-10 [XREF_BIBR - XREF_BIBR]."
19683334
reach
"It has been proposed that progesterone might also decrease NFkB mediated inflammatory transcription [6]."
17437195
ctd
No evidence text available
15866594
reach
"It has also been proposed that at an earlier step of the innate immune response, progesterone may suppress the Toll like receptors (TLR), and likewise antagonize NFkB signaling [26]."
17437195