 
            IndraLab
Statements
YOD1 inhibits cell population proliferation. 17 / 17
                        
    
      
      
      
        
      
        
      
        
      
        
      
        
      
        
      
        
      
        
      
        
      
        
      
        
      
        
      
        
      
        
      
        
      
        
      
        
      
        
      
        
      
        
      
        
      
        
      
      
    
      
      
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                                  "Therefore, our results suggest that the repression of TGF-β3-mediated transcriptional activity mediated by YOD1 RNAi may inhibit cell proliferation and migration to induce NSCL/P.In conclusion, we have shown that the downregulation of YOD1 using RNAi inhibits proliferation and migration of HOK cells, which involve inhibiting the TGF-β3 signaling pathway."
          
                              
          
                               
                            
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                                  "Studies have reported that YOD1 RNAi in Human Oral Keratinocytes can inhibit cell proliferation and migration related to the pathogenesis of nonsyndromic cleft lip with or without cleft palate (NSCL/P) through TGF-β 3 signaling [33], which suggested that the targeted inhibition of YOD1 in the advanced stage of cancer may also play a role in inhibiting cell proliferation and migration."