IndraLab

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YOD1 inhibits cell population proliferation. 5 / 5
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"Targeting YOD1 by RNA Interference Inhibits Proliferation and Migration of Human Oral Keratinocytes through Transforming Growth Factor-beta3 Signaling Pathway."
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"However , a recent study showed that downregulation of YOD1 may promote cell proliferation in cervical cancer cells [ 28 ] ."
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"Therefore, our results suggest that the repression of TGF-β3-mediated transcriptional activity mediated by YOD1 RNAi may inhibit cell proliferation and migration to induce NSCL/P.In conclusion, we have shown that the downregulation of YOD1 using RNAi inhibits proliferation and migration of HOK cells, which involve inhibiting the TGF-β3 signaling pathway."
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"Moreover, overexpression of YOD1 abrogated miR-373-induced proliferation of cervical cancer cells."
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"YOD1 RNAi may inhibit cell proliferation and migration associated with the pathogenesis of NSCL/P through TGF-beta3 signaling."
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