IndraLab

Statements



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"Notably, YOD1 knockdown significantly promoted the proliferation of tumor organoids derived from ccRCC patients (Fig. 2G)."

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"Our findings indicate that YOD1 inhibits cell proliferation in A549 cells."

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"Our findings suggest that the combined action of YOD1 and USP21 inhibits A549 cell proliferation via the Hippo signaling pathway."

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"YOD1 inhibits ccRCC cell proliferation and metastasis."

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"Moreover, YOD1 inhibited cell proliferation induced by NEDD4 in kidney cells [ 86 ]."

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"YOD1 inhibits HNSCC cell proliferation in vitro."

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"Therefore, our results suggest that the repression of TGF-β3-mediated transcriptional activity mediated by YOD1 RNAi may inhibit cell proliferation and migration to induce NSCL/P.In conclusion, we have shown that the downregulation of YOD1 using RNAi inhibits proliferation and migration of HOK cells, which involve inhibiting the TGF-β3 signaling pathway."

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"In the EdU assay, Dox-induced YOD1 significantly inhibited cell proliferation (Fig. 2D)."

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"Additionally, YOD1 knockdown notably increased the proliferation of patient-derived renal cancer organoids, as well as ccRCC proliferation and metastasis, in vitro and in vivo."

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"However , a recent study showed that downregulation of YOD1 may promote cell proliferation in cervical cancer cells [ 28 ] ."

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"These findings suggest that the synergistic effect of YOD1 and USP21 can suppress specific cancer cell proliferation by regulating the Hippo signaling pathway (Figs."

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"Targeting YOD1 by RNA Interference Inhibits Proliferation and Migration of Human Oral Keratinocytes through Transforming Growth Factor-beta3 Signaling Pathway."

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"YOD1 RNAi may inhibit cell proliferation and migration associated with the pathogenesis of NSCL/P through TGF-beta3 signaling."

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"Blocking miR-190a-3p or the overexpression of its target OTUD2/YOD1 attenuated the proliferation and migration of glioma cells [157]."

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"Notably, DEX treatment could downregulate YOD1 expression via increasing miR-520a-3p expression, thereby suppressing cell proliferation and cell adhesion, and elevating cell apoptosis in osteosarcoma [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"IHC staining showed that the expression of E-cadherin and TRIM33 was enhanced while the levels of N-cadherin and Ki67 decreased in the control group (Fig. 6E), indicating that YOD1 inhibited EMT and the proliferation of HNSCC cells."

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"Studies have reported that YOD1 RNAi in Human Oral Keratinocytes can inhibit cell proliferation and migration related to the pathogenesis of nonsyndromic cleft lip with or without cleft palate (NSCL/P) through TGF-β 3 signaling [33], which suggested that the targeted inhibition of YOD1 in the advanced stage of cancer may also play a role in inhibiting cell proliferation and migration."