IndraLab

Statements

USP28 binds E3_Ub_ligase. 3 / 3
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"The complex deubiquitinase enzyme USP28-ubiquitin ligase FBW7 plays a crucial role in regulating the stability of proteins, particularly those involved in cell signaling and cell cycle control."
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"USP28 also binds the E3 ubiquitin ligase FBW7 to stabilize MYC and promote cell proliferation [33] ( Fig. 3 a)."
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"A deubiquitinase USP28 binds to the SCF Fbw7 ubiquitin E3 ligase, stabilizing Myc, and therefore promoting cell proliferation [ xref ]."
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