IndraLab

Statements

USP9X activates YAP1. 4 / 4
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"Taken together, these results suggest that USP9X directly regulates YAP1 stability."
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"Moreover, overexpression of USP9X, dramatically increased YAP1 stabilization (XREF_SUPPLEMENTARY), while overexpression of the CS mutant decreased YAP1 stability."
29449692
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"In this study, we demonstrate that USP9X may target YAP1 for deubiquitination and stabilization, thereby promoting breast cancer growth and tumor progression."
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"Mechanistically, it was found that hsa_circ_0024093 could regulate the expression of USP9X, which further induced YAP1 deubiquitination to stabilize YAP1 protein."
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