IndraLab

Statements

Bqt1 binds USP39. 9 / 9
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"Thus, Bqt1 alone associates with Sad1 but is not sufficient to connect Sad1 to Rap1."
16615890
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"When Sad1 was overexpressed in these cells, the protein was observed along to the nuclear envelope rather than just at the SPB, and Bqt1 was also observed at the nuclear envelope ( Figure 4 E), which [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
16615890
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"Similarly, Bqt1 binds to the SPB component Sad1 [19] ."
17905509
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"In the absence of Bqt1, Bqt2-GFP showed diffuse staining throughout the nucleus and was not localized at the telomere nor at the SPB ( Figure 3 D), indicating that Bqt2 localization at either the telo[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
16615890
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"Taken together, these results showed that Bqt1 directly binds to Bqt2 and to Sad1 and that Bqt2 binds to Sad1 through interaction with Bqt1."
16615890
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"Our results demonstrate that Bqt1 and Bqt2 together form a bridge between Sad1 and Rap1: Bqt1 binds to Sad1, Bqt2 bind to Bqt1, and a complex of Bqt1 and Bqt2 binds to Rap1."
16615890
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"Two-hybrid and coimmunoprecipitation experiments showed that Bqt1 directly binds the SPB component Sad1."
16615884
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"Bqt2 lacks this ability but binds Sad1 bound Bqt1."
16615884
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"These results provide an initial scheme for connecting telomeres with the SPB: Sad1 binds Bqt1, which recruits Bqt2, forming the complex that binds Rap1, thus gluing the Rap1 bound telomere to Sad1 ( [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
16615884