IndraLab

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THBS1 binds LRP8. 6 / 6
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"Recently, it was also shown that thrombospondin-1 binds to Apoer2 and VLDLR in the brain where it participates in the chain migration of postnatal neurons along the rostral stream."
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"Similarly, we identified Thrombospondin-1 (THBS1), which binds to LRP8 (a.k.a. APOER2) and VLDLR receptors, also receptors for reelin, and seems to play a role in murine postnatal neuronal migration, as well as in synaptogenesis XREF_BIBR, XREF_BIBR."
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"Blake et al reported that TSP-1 promoted neural cell migration by binding to ApoER2 in postnatal neuronal migration [XREF_BIBR]."
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"Similarly, we identified Thrombospondin-1 ( THBS1 ), which binds to LRP8 (a."
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"In contrast to these antiangiogenic phenomena, TSP-1 may also bind ApoER2 (apolipoprotein E receptor 2) and VLDLR to promote neuronal migration."
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"Thrombospondin-1 binds to ApoER2 and VLDL receptor and functions in postnatal neuronal migration."
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