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Mutated NLRP3 activates BRCC3. 1 / 1

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"Small molecule inhibitors of JAMM/MPN+ (thiolutin and holomycin) limit pyroptosis and inflammation induced by both wild-type and autoactivating NLRP3 mutants by inhibiting BRCC3 [126]."

36551253

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IndraLab

Statements

Mutated NLRP3 activates BRCC3. 1 / 1

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