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Magnesium atom inhibits KCNH2. 2 / 2
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"These results suggest that while intracellular Mg 2+ causes some voltage dependent block of the h-erg channel, Mg ` block may not necessarily account for all of the observed rectification of the insta[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Increased extracellular Mg 2+ has been shown to increase the potency of hERG block for multiple compounds (Po et al. 1999; TeBay et al. 2021) , whereas reduced internal Mg 2+ was found to reduce the potency of quinidine (Yang et al. 1997) ."
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