IndraLab

Statements

BAP1 decreases the amount of SP1. 4 / 4
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"WT BAP1 reduced the ubiquitination levels of Sp1, whereas C91A BAP1 did not reduce ubiquitination levels (Fig. 6D)."
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"The knockdown or catalytic mutant form of BAP1 abolished the ODN-induced upregulation of Sp1 and Bax expression."
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"In addition, the ectopic expression of BAP1 greatly decreased the ubiquitination level of Sp1 and the upregulation of Sp1 and Bax, whereas the catalytic mutant of BAP1 showed no apparent effect (Fig. 6B–D)."
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"OTUB1, OTUD7A, and BAP1 downregulated Sp1 and Bax expression (Fig. 5)."
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