IndraLab

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ZUP1 inhibits cell population proliferation. 6 / 6
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"(A) After HCT116 and LoVo cells were treated with DUb or DMSO for 96 h, DUb suppressed the proliferation of HCT116 and LoVo cells (n = 12)."
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"It was further demonstrated that DUb inhibited LoVo cell proliferation, migration and invasion by upregulating SIRT2."
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"We demonstrated that DUb significantly reduced the proliferation of HCT116 and LoVo cells in a dose-dependent manner (Figure 3A)."
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"We found that DUb inhibits CRC cell proliferation through up-regulating SIRT2 in CRC cells."
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"Our findings provided direct evidence that DUb has the potential to be an effective therapeutic agent for CRC.To explore how DUb inhibits CRC cell proliferation, qRT-PCR analysis was performed to determine cancer-related genes using DUb-treated CRC cells."
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"In addition, DUb significantly decreased cell proliferation in tumor tissues as detected by immunohistochemical staining for Ki67 (Figure 1C), which can be used as an index of cell proliferation."
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