IndraLab

Statements


Diarsenic trioxide decreases the amount of KCNH2. 8 / 8
6 | 2

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"Further investigation using western blot analysis and reverse transcription-quantitative polymerase chain reaction revealed that As2O3 downregulated hERG expression via upregulation of miR-328 expression in MCF-7 cells."

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"The combination of As2O3 with resveratrol, on the one hand reduced the expression of hERG channels on the membrane, and on the other hand weaken the binding between hERG and integrin beta 1, which may be the main cause of downstream signaling pathways alterations, including the activation of the apoptotic pathway."

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No evidence text available