IndraLab

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HCN4 activates Phase IV. 1 / 1

| 1

reach

"The modulation of HCN4 gating would then increase Phase IV slope of the cardiac action potential and allow for earlier opening of L-type Ca 2+ channels, causing the sinoatrial node to " fire " more frequently in the presence of epinephrine and norepinephrine and with reductions of acetylcholine."

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INDRA sources:

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IndraLab

Statements

HCN4 activates Phase IV. 1 / 1

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